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Participants can choose a full 4-day package, or a 2-day domestic or international package.An exceptional early bird rate awaits Members of the Malaysian Bar (until ). In the study described in the current report, we compared the year-to-year variations in ETEC isolates expressing enterotoxins and the CF types over a 3- year period, beginning in September 2000, with special emphasis paid to the four most significantly expressed ETEC CFs.In addition, we examined the genomic profile of ETEC using Xba I macrorestriction profiling and pulsed-field gel electrophoresis (PFGE) to determine whether there was an association between specific strains and pathogenicity.Between September 2000 and August 2003, surveillance was established at the Benha Fever Hospital and Abu Homos General Hospital in the Nile Delta of Egypt (53).Due to the large number of children who come to the hospitals for evaluation of diarrhea, the study enrollment was limited to every fifth child whose primary complaint was diarrhea.ETEC isolates may express a single detectable CF, as is the case for CFA/I, or multiple CFs, such as that observed with CS3 (CS3 alone or in combination with CS1 or CS2) and CS6 (CS6 alone or in combination with CS4 or CS5).In Egypt, several community-based studies have reported on the burden of ETEC infection in native children and foreign travelers (2, 34).
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To date, more than 20 ETEC CFs have been characterized (11, 27).
The diversity of ETEC CFs is due to differences in the primary amino acid sequences of the adhesive fimbrial structural subunits.
The views expressed in any editorials or articles published are not necessarily the views of the Bar Council.
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